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EPITHALON - Research Grade Peptide

EPITHALON - Research Grade Peptide

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EPITHALON – Research-Grade Synthetic Tetrapeptide

For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, consumption, clinical use or therapeutic application. It must not be used in any way that contravenes applicable laws or the requirements of the Medicines and Healthcare products Regulatory Agency.

  • Research-grade synthetic tetrapeptide with batch documentation available where supplied
  • Defined linear peptide sequence comprising four amino-acid residues
  • Chromatographic purity of at least 99% where confirmed by the applicable batch Certificate of Analysis
  • Supplied as lyophilised laboratory material in sealed flip-top headspace vials
  • Batch identity, chromatographic purity, peptide content and analytical specifications stated in the applicable Certificate of Analysis
  • Handled and supplied exclusively as a research-use laboratory material

All of our research peptides and related laboratory materials are supplied strictly for scientific research and laboratory use only. Each vial contains lyophilised material prepared to support consistent laboratory handling and storage. The stated nominal amount refers to the declared Epithalon peptide content of a single vial, subject to the applicable batch documentation. Where dissolution or reconstitution is required, the solvent, buffer, concentration, handling procedure and storage conditions stated in the applicable Certificate of Analysis, Safety Data Sheet or validated laboratory method should be followed. We do not provide advice or recommendations concerning dosage, administration or use in humans or animals.

Premium ULTIMATE Laboratory Specification

ULTIMATE EPITHALON

Enhanced Peptide Purification and More Stringent LPS Testing

Additional preparative high-performance liquid chromatography purification and a more stringent bacterial endotoxin and lipopolysaccharide testing specification for demanding scientific laboratory workflows.

The ULTIMATE Epithalon range is our premium research specification for laboratories requiring an enhanced level of peptide purification and quality control. Following the standard synthesis and purification process, the finished Epithalon research material undergoes an additional preparative high-performance liquid chromatography purification stage designed to reduce residual synthesis-related and process-related impurities further. ULTIMATE batches are also assessed under a more stringent bacterial endotoxin and lipopolysaccharide testing specification, with the applicable analytical and batch documentation provided where supplied.

Additional HPLC Purification
A further preparative high-performance liquid chromatography purification stage is completed after the standard peptide purification workflow.
More Stringent LPS Testing
Assessed under the enhanced ULTIMATE bacterial endotoxin and lipopolysaccharide testing specification.
Premium Research Specification
Intended for laboratory projects requiring additional peptide purification and an enhanced quality-control specification.
Regular or ULTIMATE?
For the majority of routine analytical, investigative and general laboratory work, our Regular research-grade Epithalon product remains highly suitable and provides an appropriate balance of peptide quality, batch documentation and value. The ULTIMATE option is intended for scientific projects where the additional preparative high-performance liquid chromatography purification stage and more stringent bacterial endotoxin and lipopolysaccharide testing specification are specifically required.

ULTIMATE Epithalon remains strictly for scientific laboratory research and analytical use only. It is not intended for human or animal use, clinical use, diagnostic use or therapeutic application. Identity, sequence, chromatographic purity, peptide content, molecular form, counter-ion content, bacterial endotoxin results and other analytical specifications are batch-specific and should be confirmed using the applicable Certificate of Analysis.

Chemical Information:

  • Product Name: EPITHALON
  • Preferred Database Name: Epitalon
  • Alternative Names: Epithalon; AEDG peptide; Ala-Glu-Asp-Gly
  • Identity Clarification: Epithalamin or Epithalamine is a different pineal-derived polypeptide complex and is not a synonym for the synthetic Epitalon tetrapeptide
  • Chemical Classification: Synthetic linear tetrapeptide
  • Sequence Length: Four amino-acid residues
  • Peptide Sequence: H-Ala-Glu-Asp-Gly-OH
  • One-Letter Sequence: AEDG
  • Sequence-Based Chemical Name: L-alanyl-L-glutamyl-L-aspartylglycine
  • N-Terminal Structure: Free amino terminus
  • C-Terminal Structure: Free carboxylic acid terminus
  • Free-Form CAS Number: 307297-39-8
  • PubChem Compound Identifier: CID 219042
  • Unique Ingredient Identifier: O65P17785G
  • Free-Form Molecular Formula: C14H22N4O9
  • Free-Form Average Molecular Weight: Approximately 390.35 g/mol
  • Epitalon Acetate CAS Number: 307297-40-1
  • Epitalon Acetate Molecular Formula: C14H22N4O9 · C2H4O2, equivalent to C16H26N4O11
  • Epitalon Acetate Average Molecular Weight: Approximately 450.40 g/mol
  • Purity Specification: At least 99% chromatographic purity where confirmed by the applicable batch Certificate of Analysis and stated analytical method
  • Physical Form: Lyophilised laboratory material, as stated in the applicable batch Certificate of Analysis
  • Appearance: Refer to the applicable batch Certificate of Analysis
  • Chemical-Form Confirmation: The applicable Certificate of Analysis should identify whether the supplied material is Epitalon free form, Epitalon acetate or another counter-ion form
  • Counter-Ion Confirmation: Acetate, trifluoroacetate or another counter-ion may affect the formula weight, water content and net peptide content of the supplied laboratory material
  • Analytical Interpretation: Chromatographic purity, molecular identity, net peptide content, water content, residual solvent content and counter-ion content are separate analytical measurements and should be interpreted together

✓ Batch documentation – Certificate of Analysis documentation is provided where supplied for review.
✓ Certificate of Analysis – Accessible through the product QR code where provided for the applicable batch.
✓ Safety Data Sheet – Supplied to support appropriate laboratory handling, storage and regulatory compliance.
✓ Sequence documentation – Peptide sequence and molecular identity should be confirmed using the applicable batch records.
✓ Analytical identity documentation – Molecular identity should be supported by appropriate analytical data for the applicable batch.
✓ Purity documentation – The reported chromatographic purity applies only to the analytical method and batch stated in the Certificate of Analysis.
✓ Peptide-content documentation – Net peptide content should be distinguished from chromatographic purity and interpreted alongside water and counter-ion results.
✓ Counter-ion documentation – Acetate, trifluoroacetate or another counter-ion should be identified and quantified where applicable.
✓ Supplier documentation – Reviewed where supporting synthesis, purification and analytical records are supplied.
✓ Fast, reliable and trackable delivery – Securely packaged and dispatched using insulated or temperature-controlled packaging where required by the applicable transport and storage specification.


For Research Use Only
This product is supplied strictly for scientific research, laboratory analysis and experimental work. It is not intended for human consumption, animal use, clinical use, diagnostic use or any form of therapeutic application.


Epithalon Product Overview

Our Epithalon research-grade synthetic tetrapeptide, also known as Epitalon or the AEDG peptide, is supplied for controlled scientific laboratory investigation, analytical method development, peptide characterisation, high-performance liquid chromatography assessment and mass-spectrometry workflows. The material comprises a defined linear sequence of four amino-acid residues with free amino and carboxylic acid termini.

The material is handled with a focus on batch traceability, documented quality control and consistent laboratory presentation. Product identity, chromatographic purity, net peptide content, molecular form, amino-acid sequence, counter-ion content, water content, residual solvents, bacterial endotoxin results and other analytical specifications should be confirmed using the applicable batch Certificate of Analysis. Chromatographic purity should not automatically be interpreted as equivalent to the total net peptide content of the vial.

For the majority of routine analytical, investigative and general laboratory work, the Regular Epithalon specification remains highly suitable. The premium black-and-gold ULTIMATE Epithalon option provides an additional preparative high-performance liquid chromatography purification stage and a more stringent bacterial endotoxin and lipopolysaccharide testing specification for scientific projects requiring enhanced quality-control parameters.

View Certificate of Analysis

View Safety Data Sheet

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