N-ACETYL EPITALON - Research Grade Peptide

N-ACETYL EPITALON – Research-Grade N-Acetylated Tetrapeptide

For research purposes only. This product is supplied exclusively for scientific laboratory research and analytical purposes. It is not intended for human or animal use, consumption, clinical use or therapeutic application. It must not be used in any way that contravenes applicable laws or the requirements of the Medicines and Healthcare products Regulatory Agency.

• Research-grade N-acetylated tetrapeptide with batch documentation available where supplied
• Defined Ala-Glu-Asp-Gly tetrapeptide sequence containing a covalent N-terminal acetyl modification
• Free carboxylic acid C-terminal structure unless expressly stated otherwise in the applicable batch documentation
• Supplied as lyophilised laboratory material in sealed flip-top headspace vials
• Batch identity, chromatographic purity, peptide content and analytical specifications stated in the applicable Certificate of Analysis
• Handled and supplied exclusively as a research-use laboratory material

All of our research peptides and related laboratory materials are supplied strictly for scientific research and laboratory use only. Each vial contains lyophilised material prepared to support controlled laboratory handling and storage. The stated nominal amount refers to the declared N-Acetyl Epitalon peptide content of a single vial, subject to the applicable batch documentation. Where dissolution or reconstitution is required, the solvent, buffer, concentration, handling procedure and storage conditions stated in the applicable Certificate of Analysis, Safety Data Sheet or validated laboratory method should be followed. We do not provide advice or recommendations concerning dosage, administration or use in humans or animals.

Chemical and Structural Information:

• Product Name: N-ACETYL EPITALON
• Preferred Substance Name: N-Acetyl Epitalon
• Alternative Names: N-Acetyl Epithalon; N-Acetyl AEDG; Ac-AEDG-OH; N-Acetylated Epitalon
• Material Classification: Synthetic N-terminally acetylated linear tetrapeptide
• Sequence Length: Four amino-acid residues
• Core Peptide Sequence: Ala-Glu-Asp-Gly
• One-Letter Core Sequence: AEDG
• Complete Structural Shorthand: Ac-Ala-Glu-Asp-Gly-OH
• Modified Sequence Shorthand: Ac-AEDG-OH
• Sequence-Based Chemical Name: N-acetyl-L-alanyl-L-alpha-glutamyl-L-alpha-aspartylglycine
• N-Terminal Structure: Covalently N-acetylated alanine
• C-Terminal Structure: Free glycine carboxylic acid terminus
• Acetylation Clarification: The N-terminal acetyl group is part of the covalent peptide structure and should not be confused with an acetate counter-ion
• CAS Registry Number: No verified CAS Registry Number was located for this exact N-acetyl free-acid structure in the referenced FDA Global Substance Registration System-linked PubChem identity record
• PubChem Compound Identifier: CID 171390141
• Unique Ingredient Identifier: UXR7AF6R4F
• Molecular Formula: C₁₆H₂₄N₄O₁₀
• Average Molecular Weight: Approximately 432.38 g/mol
• Exact Mass: Approximately 432.1492 Da
• InChIKey: QXYAPAXZRKPASL-HGNGGELXSA-N
• Formula Basis: The molecular formula and molecular weight describe the neutral N-acetylated peptide with a free C-terminal carboxylic acid, without counter-ions, residual water, solvents or formulation excipients
• Parent Epitalon Cross-Reference: Unmodified Epitalon has the structure H-Ala-Glu-Asp-Gly-OH, CAS number 307297-39-8, molecular formula C₁₄H₂₂N₄O₉ and molecular weight approximately 390.35 g/mol
• Parent-CAS Clarification: CAS number 307297-39-8 identifies unmodified Epitalon and should not be assigned to N-Acetyl Epitalon
• Amidated-Derivative Distinction: N-Acetyl Epitalon Amide or N-Acetyl Epithalonamide has the structure Ac-Ala-Glu-Asp-Gly-NH₂ and is chemically distinct from the free-acid material described on this page
• Epitalon Acetate Distinction: Epitalon acetate is also a separate material and should not be confused with covalently N-acetylated Epitalon
• Physical Form: Lyophilised laboratory material, as stated in the applicable batch Certificate of Analysis
• Appearance: White to off-white laboratory material, subject to confirmation in the applicable batch Certificate of Analysis
• Purity Specification: The applicable chromatographic purity result, analytical method and acceptance criterion are stated in the batch Certificate of Analysis
• Peptide-Content Specification: Net N-Acetyl Epitalon peptide content should be distinguished from chromatographic purity and interpreted alongside water, counter-ion, residual-solvent and formulation results
• Sequence Confirmation: The complete four-residue AEDG sequence should be confirmed using the applicable synthesis and batch records
• N-Terminal Modification Confirmation: Product identity should confirm the covalent N-terminal acetyl group using appropriate mass-spectrometry or equivalent analytical data
• C-Terminal Confirmation: The applicable molecular-identity documentation should confirm that the glycine terminus is present as a free carboxylic acid rather than a C-terminal amide
• Mass-Spectrometry Confirmation: Molecular identity should be supported by analytical mass data consistent with the specified N-Acetyl Epitalon molecular structure
• Chemical-Form Confirmation: The applicable Certificate of Analysis should identify whether the supplied laboratory material is the neutral free-acid structure, an additional salt or counter-ion form, or a formulated lyophilised preparation
• Counter-Ion Confirmation: Sodium, ammonium, acetate, trifluoroacetate or another counter-ion may affect the total measured material mass and net peptide content of the supplied laboratory material
• Residual-Solvent Specification: Applicable residual solvents arising from peptide synthesis, acetylation, cleavage and chromatographic purification should be stated or controlled through the batch specification
• Related-Impurity Control: Unmodified Epitalon, incompletely acetylated material, deletion sequences, truncated peptides, incompletely deprotected material and other synthesis-related or process-related impurities are separate quality attributes
• Endotoxin Specification: The applicable bacterial endotoxin or LPS result, analytical method, reporting units, method-suitability controls and acceptance criterion should be stated in the batch Certificate of Analysis
• Analytical Interpretation: Molecular identity, amino-acid sequence, N-terminal acetylation, C-terminal structure, chromatographic purity, net peptide content, water content, residual solvents, counter-ion content and bacterial endotoxin results are separate analytical measurements and should be interpreted together

✓ Batch documentation – Completed Certificate of Analysis documentation is provided where supplied for the applicable batch.
✓ Certificate of Analysis – Accessible through the product QR code where a completed batch-specific document has been published.
✓ Safety Data Sheet – Supplied to support appropriate laboratory handling, storage and regulatory compliance.
✓ Sequence documentation – The complete AEDG tetrapeptide sequence should be confirmed using the applicable batch and synthesis records.
✓ N-terminal modification documentation – Covalent N-terminal acetylation should be supported by appropriate molecular-identity data.
✓ C-terminal structure documentation – The free carboxylic acid terminus should be distinguished from a C-terminally amidated derivative.
✓ Mass-spectrometry documentation – Molecular identity should be supported by analytical mass data consistent with the specified N-Acetyl Epitalon structure.
✓ Purity documentation – The reported chromatographic purity applies only to the analytical method and batch stated in the Certificate of Analysis.
✓ Peptide-content documentation – Net N-Acetyl Epitalon content should be distinguished from chromatographic purity and interpreted alongside water, counter-ion and residual-solvent results.
✓ Chemical-form documentation – The neutral free-acid structure, additional salt form or formulated material should be identified clearly in the applicable product and batch records.
✓ Bacterial endotoxin documentation – The applicable bacterial endotoxin or LPS result should identify the test method, reporting units, method-suitability controls and acceptance criterion.
✓ Supplier documentation – Reviewed where supporting synthesis, N-terminal acetylation, purification and analytical records are supplied.
✓ Fast, reliable and trackable express delivery – Securely packaged and dispatched using insulated or temperature-managed packaging where required by the applicable transport and storage specification.

For Research Use Only
This product is supplied strictly for scientific research, laboratory analysis and experimental work. It is not intended for human consumption, animal use, clinical use, diagnostic use or any form of therapeutic application.

N-Acetyl Epitalon Product Overview

Our N-Acetyl Epitalon research-grade synthetic tetrapeptide is supplied for controlled scientific laboratory investigation, analytical method development, modified peptide characterisation, high-performance liquid chromatography assessment, mass-spectrometry workflows and reference-material comparison. The material comprises the defined Ala-Glu-Asp-Gly tetrapeptide sequence containing a covalently attached N-terminal acetyl group and a free C-terminal carboxylic acid.

The N-terminal acetyl modification changes the molecular identity and formula relative to unmodified Epitalon. Product identity testing should therefore distinguish N-Acetyl Epitalon from unmodified Epitalon, incompletely acetylated material, N-Acetyl Epitalon Amide and any additional salt or counter-ion form.

The material is handled with a focus on batch traceability, documented quality control and consistent laboratory presentation. Product identity, amino-acid sequence, N-terminal acetylation, C-terminal structure, chromatographic purity, net peptide content, molecular form, counter-ion content, water content, residual solvents, bacterial endotoxin results and other analytical specifications should be confirmed using the applicable batch Certificate of Analysis.

The molecular formula C₁₆H₂₄N₄O₁₀ and average molecular weight of approximately 432.38 g/mol describe N-Acetyl Epitalon with the structure Ac-Ala-Glu-Asp-Gly-OH. CAS number 307297-39-8, formula C₁₄H₂₂N₄O₉ and molecular weight approximately 390.35 g/mol describe unmodified Epitalon and should not be applied to this N-acetylated product.

The term “N-acetyl” describes a covalent modification to the peptide terminus and does not establish that the supplied material is an acetate salt. Any additional acetate, trifluoroacetate, sodium, ammonium or other counter-ion content should be identified separately in the applicable batch documentation.

Chromatographic purity should not automatically be interpreted as equivalent to total net peptide content. Likewise, a bacterial endotoxin or LPS result does not establish sterility, molecular identity, correct N-terminal acetylation, C-terminal structure or the absence of every synthesis-related and process-related impurity.

For the majority of routine analytical, chromatographic, modified peptide-characterisation and general laboratory work, the Regular N-Acetyl Epitalon specification remains highly suitable. The premium black-and-gold ULTIMATE N-Acetyl Epitalon option provides an additional preparative high-performance liquid chromatography purification stage and a more stringent bacterial endotoxin and lipopolysaccharide testing specification for scientific projects requiring enhanced quality-control parameters.

View Certificate of Analysis

View Safety Data Sheet